Tolovana Lodge (Tolovana Roadhouse as it is known historically) is located 53 miles by trail from Nenana, AK. It is most famous for being the first stop in The Serum Run of 1925 – a sled dog relay which brought the diphtheria antitoxin to Nome to save the lives of many children during this historical epidemic. The Serum Run was a precursor to the modern-day Iditarod Sleddog Race which follows much of the original relay route. Due to lack of snow in Anchorage (the traditional Iditarod race start since 1973), the 2015 and 2017 Iditarod Sled Dog Race starts were moved to Fairbanks and Tolovana Roadhouse provided a hospitality stop for mushers during these years.
Tolovana has a rich history as a Roadhouse circa 1925 and prior to that as a Trading Company providing staples and wood for boilers on steamships headed down the Tanana and to the goldfields up the Tolovana to Livengood. Circa 1917 the land also housed a telegraph office (you can still see the telegraph wire and insulators hanging in trees along the trail). And prior to white settlement, the area was traditional Athabascan hunting and fishing grounds.